MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) is\u00a0a 16-amino acid mitochondrial-derived peptide that acts as a potent metabolic regulator to enhance insulin sensitivity, metabolic flexibility, and physical performance. It functions by activating the AMPK pathway and is explored for anti-aging, obesity treatment, and cellular stress resilience.<\/p>\n
Key Characteristics and Functions:
\n\u2022\u00a0\u00a0\u00a0\u00a0Origin:\u00a0Encoded by mitochondrial DNA (mtDNA), not nuclear DNA, acting as a signaling molecule between mitochondria and the nucleus.
\n\u2022\u00a0\u00a0\u00a0\u00a0Mechanism of Action:\u00a0Activates AMP-activated protein kinase (AMPK), a master regulator of cellular energy, to enhance glucose uptake and fatty acid oxidation.
\n\u2022\u00a0\u00a0\u00a0\u00a0Metabolic Impact:\u00a0Improves insulin sensitivity, reduces fat accumulation in the liver, and increases mitochondrial function.
\n\u2022\u00a0\u00a0\u00a0\u00a0Anti-Aging and Performance:\u00a0Studies show it can reverse age-dependent declines in physical capacity and is induced by exercise.
\n\u2022\u00a0\u00a0\u00a0\u00a0Target Tissues:\u00a0Primarily acts on skeletal muscle, though it also impacts adipose tissue.<\/p>\n
Common Uses in Research\/Therapy:
\n\u2022\u00a0\u00a0\u00a0\u00a0Weight Management:\u00a0Often researched for its ability to reduce obesity and improve metabolic health.
\n\u2022\u00a0\u00a0\u00a0\u00a0Diabetes Management:\u00a0Helps regulate glucose metabolism, particularly in insulin resistance.
\n\u2022\u00a0\u00a0\u00a0\u00a0Anti-Aging:\u00a0Promotes cellular resilience and energy homeostasis.<\/p>\n","protected":false},"excerpt":{"rendered":"
40mg Vial<\/strong><\/p>\n Contents: MOTS-C
\nForm: Lyophilized powder
\nPurity: >98%<\/p>\n","protected":false},"featured_media":287,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[20,18],"product_tag":[],"class_list":["post-53","product","type-product","status-publish","has-post-thumbnail","product_cat-longevity","product_cat-weight-loss","first","instock","shipping-taxable","purchasable","product-type-simple"],"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/aminolabsma.com\/index.php?rest_route=\/wp\/v2\/product\/53","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/aminolabsma.com\/index.php?rest_route=\/wp\/v2\/product"}],"about":[{"href":"https:\/\/aminolabsma.com\/index.php?rest_route=\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/aminolabsma.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=53"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/aminolabsma.com\/index.php?rest_route=\/wp\/v2\/media\/287"}],"wp:attachment":[{"href":"https:\/\/aminolabsma.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=53"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/aminolabsma.com\/index.php?rest_route=%2Fwp%2Fv2%2Fproduct_brand&post=53"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/aminolabsma.com\/index.php?rest_route=%2Fwp%2Fv2%2Fproduct_cat&post=53"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/aminolabsma.com\/index.php?rest_route=%2Fwp%2Fv2%2Fproduct_tag&post=53"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}